Wayne State University

Aim Higher

School of Medicine

Profile

Professor, Research Educator
Full Time
Research Laboratory Instruction
Louis M. Elliman Clinical Research Building
421 E. Canfield, Rm: 2146
Detroit, MI 48201
Biography

Dr. Li Li received her BS degree from University of Science and Technology of China in 1985; she went on to obtain a Ph.D in Molecular Biology and Biochemistry from University of Texas at Houston in 1991. In 1996, she joined the faculty at Wayne State University as an assistant professor.

Current Academic and Professional Appointments

  • Professor, Department of Internal Medicine & Center for Molecular Medicine and Genetics, Wayne State University

Professional Organization Memberships/Involvements

  • American Heart Association
  • Chinese American Heart Association
  • North American Vascular Biology Organization
  • The American Physiological Society
  • National Marfan Foundation
     
Research

Investigating the molecular mechanisms of smooth muscle phenotypic modulation in vascular diseases such as atherosclerosis and aneurysms using tissue culture cells and transgenic/knockout mouse models. Particular interests include transcriptional regulation and the role of SM22, an actin binding cytoskeleton protein in smooth muscle cell phenotypic modulation in response to injury signals. Her lab has been using comprehensive cellular, molecular and genetic approaches to address these issues. Understanding the molecular mechanisms of cardiovascular development is critical for developing therapeutic strategies for human vascular diseases.